PF-04995274
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-18137-100 mg |
| CAS # | 1331782-27-4 |
| Pricing | 100 mg, USD $650.0 |
| Biological Activity | PF-04995274 is a potent, high-affinity, orally active and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 has an EC50 range of 0.26-0.47 nM for human 5-HT4A/4B/4D/4E (Ki range of 0.15-0.46 nM), and has an EC50 range of 0.59-0.65 nM for rat 5-HT4S/4L/4E (Ki of 0.30 nM for rat 5-HT4S). PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease[1][2][3]. |
| Purity | 99.42% |
| MWt | 432.51 |
| Formula | C₂₃H₃₂N₂O₆ |