AX-024
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-107390-25 mg |
| CAS # | 1370544-73-2 |
| Pricing | 25 mg, USD $636.0 |
| Biological Activity | AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A. |
| Purity | ≥98.0% |
| MWt | 339.4 |
| Formula | C₂₁H₂₂FNO₂ |