Ralimetinib dimesylate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13241-10 mM * 1 mL |
| CAS # | 862507-23-1 |
| Pricing | 10 mM * 1 mL, USD $121.0 |
| Synonyms | LY2228820 dimesylate |
| MWt | 612.74 |
| Formula | C₂₆H₃₇FN₆O₆S₂ |
| Biological Activity | Ralimetinib dimesylate (LY2228820 dimesylate) is a selective, ATP-competitive inhibitor of p38 MAPK α/β with IC50s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38a MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. |
| Purity | 99.52% |