IDH-305
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-104036-10 mM * 1 mL |
| CAS # | 1628805-46-8 |
| Pricing | 10 mM * 1 mL, USD $363.0 |
| Biological Activity | IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1 (R132) mutation. IDH-305 exhibits greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC50= 27 nM (IDH1R132H), 28 nM (IDH1R132C), 6.14 µM (IDH1WT))[1][2]. |
| Purity | ≥98.0% |
| MWt | 490.45 |
| Formula | C₂₃H₂₂F₄N₆O₂ |