TH5487
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-125276-10 mg |
| CAS # | 2304947-71-3 |
| Pricing | 10 mg, USD $200.0 |
| Biological Activity | TH5487 is a potent 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor with an IC50 of 342 nM. TH5487 stops OGG1 from recognizing its DNA substrate, inhibits DNA repair and modifies OGG1 chromatin dynamics, which results in the inhibition of proinflammatory pathway genes[1]. |
| Purity | 98.10% |
| MWt | 541.18 |
| Formula | C₁₉H₁₈BrIN₄O₂ |