Wedelolactone
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-N0551-10 mM * 1 mL |
| CAS # | 524-12-9 |
| Pricing | 10 mM * 1 mL, USD $55.0 |
| Biological Activity | Wedelolactone, a natural product from Ecliptae herba, suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK Complex[1]. Wedelolactone inhibits 5-lipoxygenase (5-Lox) (IC50~2.5 μM) activity by an oxygen radical scavenging mechanism. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt[2]. Anti-cancer, anti-inflammatory, and antioxidant activities[3]. |
| Purity | 99.91% |
| MWt | 314.25 |
| Formula | C₁₆H₁₀O₇ |