E7449
Supplier | MedChemExpress |
---|---|
Product # | HY-12418-50 mg |
CAS # | 1140964-99-3 |
Pricing | 50 mg, USD $900.0 |
Biological Activity | E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ∼50 and ∼50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate. |
Purity | ≥98.0% |
MWt | 317.34 |
Formula | C₁₈H₁₅N₅O |