O6-Benzylguanine
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-W002585-10 mM * 1 mL |
| CAS # | 19916-73-5 |
| Pricing | 10 mM * 1 mL, USD $27.0 |
| Biological Activity | O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity[1][2]. |
| Purity | 99.63% |
| MWt | 241.25 |
| Formula | C₁₂H₁₁N₅O |