OSU-T315
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-18676-10 mg |
| CAS # | 2070015-22-2 |
| Pricing | 10 mg, USD $500.0 |
| Biological Activity | OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain)[1]. OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner[2]. OSU-T315 causes cell death through apoptosis and autophagy[1]. |
| Purity | ≥98.0% |
| MWt | 533.59 |
| Formula | C₃₀H₃₀F₃N₅O |