Doramapimod
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10320-100 mg |
| CAS # | 285983-48-4 |
| Pricing | 100 mg, USD $185.0 |
| Synonyms | BIRB 796 |
| MWt | 527.66 |
| Formula | C₃₁H₃₇N₅O₃ |
| Biological Activity | Doramapimod (BIRB 796) is an orally active, highly potent p38 MAPK inhibitor, which has an IC50 for p38α=38 nM, for p38β=65 nM, for p38γ=200 nM, and for p38δ=520 nM. Doramapimod has picomolar affinity for p38 kinase (Kd=0.1 nM). Doramapimod also inhibits B-Raf with an IC50 of 83 nM[1][2]. |
| Purity | 99.88% |