SK1-I
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-119016-10 mg |
| CAS # | 1072443-89-0 |
| Pricing | 10 mg, USD $580.0 |
| Biological Activity | SK1-I (BML-258), an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a Ki value of 10 µM[1]. SK1-I shows no activity at SPHK1 PKCα, PKCδ, PKA, AKT1, ERK1, EGFR, CDK2, IKKβ or CamK2β. SK1-I enhances autophagy and has antitumor activity[2]. |
| Synonyms | BML-258 |
| MWt | 277.4 |
| Formula | C₁₇H₂₇NO₂ |