PD98059
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12028-100 mg |
| CAS # | 167869-21-8 |
| Pricing | 100 mg, USD $228.0 |
| Biological Activity | PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 µM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 µM) and MEK2 (IC50 of 50 µM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR transformation (IC50 of 1 μM). PD98059 also inhibits autophagy[1][2][3]. |
| Purity | 99.94% |
| MWt | 267.28 |
| Formula | C₁₆H₁₃NO₃ |