SW155246
SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1) with IC50 value of 1.2 μM, displaying 30-fold selectivity for inhibition of human DNMT1 versus human or murine DNMT3A or -3B. It was shown to inhibit global methylation in HeLa cells, and reactivate expression of the tumor suppressor gene RASSF1A in A549 cells.
| Supplier | BOC Sciences |
|---|---|
| Product # | 420092-79-1 |
| Pricing | Inquire |
| Cas | 420092-79-1 |
| Molecular Weight | 378.8 |
| Molecular Formula | C16H11ClN2O5S |
| Canonical SMILES | C1=CC=C2C(=C1)C(=CC=C2O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-] |