BTRX-335140

• Supplier: MedChemExpress
• Product #: HY-124754-10 mM * 1 mL
• CAS #: 2244614-14-8
• Synonyms: CYM-53093
• MWt: 453.55
• Formula: C₂₅H₃₂FN₅O₂
• Biological Activity:
  • BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively.
  • BTRX-335140 endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. BTRX-335140 can distribute well into the CNS. ADMET (absorption, distribution, metabolism, excretion, and toxicity) [1].
• Purity: 99.71%