GSK864
GSK864 is a cell penetrant, selective allosteric inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant with IC50 values of 8.8, 15.2 and 16.6 nM for IDH1 mutants R132C, R132H, and R132G, respectively.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1816331-66-4 |
| Pricing | Inquire |
| Cas | 1816331-66-4 |
| Molecular Weight | 558.6 |
| Molecular Formula | C30H31FN6O4 |
| Canonical SMILES | CC1=CC(=CC(=C1OC)C)NC(=O)C2=NN(C3=C2CN(CC3(C)C(=O)N)C(=O)C4=CC=CN4)CC5=CC=C(C=C5)F |